The Lyon Real World Evidence in Metastatic NeuroEndocrine Tumours
Neuroendocrine tumours (NETs) are rare and include a heterogeneous group of neoplasms derived
from the endocrine system found in the gastrointestinal tract, pancreas and lung.
Gastroenteropancreatic (GEP) NETs represent the majority of neuroendocrine neoplasms (NEN)
and the annual incidence of all GEP-NETs has been estimated to 6.98 per 100,000 person-years
in 2012 and is steadily rising. While data on the incidence of metastatic GEP-NET is limited,
more than 50% of patients with GEP-NET have metastatic disease at the time of diagnosis.
Incorrect and delayed diagnoses are still common. Treatment options include surgery,