Tryptophan Metabolism in Human Brain Tumors
In this research study, we will track the build-up of tryptophan, a radioactive tracer, in
the brain using positron emission tomography (PET) scanning. Tryptophan, in its natural
state, is an amino acid (one of the building blocks of proteins) that is normally present in
the brain, and is used by the brain cells to create various other compounds. This process is
altered in the presence of a brain tumor. By using a form of tryptophan marked with a small
amount of radiation, we will be able to track this process during the course of the PET scan.
This research will help determine if AMT PET is a useful method to recognize and