Advanced MRI for Posterior Fossa Tumours
Post-operative paediatric cerebellar mutism syndrome (pCMS) is a well-recognised complication
of resective surgery for brain tumours of the cerebellum and fourth ventricle in children.
Occurring in around 25% of infratentorial craniotomies, it is characterised by a delayed
onset of mutism and emotional lability, and may comprise motoric and cognitive cerebellar
deficits. Transient mutism gives way to prolonged, and often incomplete, recovery.
Neuroimaging studies are beginning to reveal anatomical and functional aberrancies in the
brain of children with pCMS. The cerebellar efferent pathways are likely to be implicated as