Risk Factors at Chronic Non-communicable Diseases in People of Working Age

Study Purpose

Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests, electrocardiography and ultrasound imaging, to develop a corporate prevention program for the company to reduce the risk of complications of NCDs. Research stages: 1. Questionnaire to identify socio-demographic, behavioral, hereditary, psycho-emotional risk factors of NCDs. 2. Laboratory tests (analysis of glucose and cholesterol in the capillary blood, detection of microalbuminuria), diagnostic tests (electrocardiography, and carotid artery ultrasound) 3. Evaluation of the results of questionnaires and surveys. Recommendations for lifestyle modification and follow-up in a local healthcare department

Recruitment Criteria

Accepts Healthy Volunteers Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms	Yes
Study Type An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies.	Observational
Eligible Ages	18 Years and Over
Gender	All

More Inclusion & Exclusion Criteria

Inclusion Criteria:

- employees of the company.

- persons without NCDs diagnosis and not receiving permanent medication.

- residents of the region of the Russian Federation where a factory with permanent or temporary registration is located.

Exclusion Criteria:

- refusal to sign informed consent.

- any NCDs requiring constant medication.

- active cancer.

- pulmonary embolism.

- valve defects of the heart (except secondary mitral regurgitation)

Trial Details

Trial ID: This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.	NCT06812767
Phase Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.
Lead Sponsor The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.	National Medical Research Center for Therapy and Preventive Medicine
Principal Investigator The person who is responsible for the scientific and technical direction of the entire clinical study.	Olga Dzhioeva, MD, PhD
Principal Investigator Affiliation	National Medical Research Center for Therapy and Preventive Medicine
Agency Class Category of organization(s) involved as sponsor (and collaborator) supporting the trial.	Other
Overall Status	Enrolling by invitation
Countries	Russia
Conditions The disease, disorder, syndrome, illness, or injury that is being studied.	Chronic Non-communicable Disease

Additional Details

Currently the emphasis in preventive medicine is also on health of the working population, which is a key state policy in the Russian Federation. Health of working citizens is an important factor in the development and safety of the production sector, but it is also the key to health and well-being of all other groups

- children and older generations - that is, in fact, the fundamental factor for social development.

Therefore, the integration of health-saving technologies into all areas of working life, including production and work activities, is particularly important. In today's world, it is very important that everyone actively participate in the preservation the health of the individual and its high awareness. Awareness of risk factors for chronic non-communicable diseases and measures prevention throughout life is an important part of a healthy society. Monitoring the health of working citizens allows to predict the problem and take the necessary measures in a timely manner. In the Russian Federation, medical screening is a complex system, including medical examination by physicians of several specialties and application of the necessary methods of examination to identify chronic non-communicable diseases and their risk factors at an early stage that are the main cause of disability and premature mortality in the country's population, and also to form health status groups and provide recommendations for patients. The examination is carried out once every three years and includes a set of methods of advanced examination to identify early on the most likely chronic non-communicable disease for a given age and gender. Regular checkups are the most important mass and highly effective medical technology of health savings. The work of carrying out regular preventive examinations and check-ups is carried out by primary health care. Often the quality of such work is limited by manpower shortages, technological and logistical barriers. In modern conditions, these obstacles can be overcome by using mobile systems that include modern digital diagnostic technologies, Allow for more in-depth investigation and identification of risk factors not covered by the standard examination protocol. This will increase the coverage and detection of risk factors, which is an important component of the health saving of the working population

Arms & Interventions

Arms

: Persons without NCDs

Persons without known NCDs and not using any medication on a permanent basis

Interventions

Diagnostic Test: - electrocardiography

12 standard leads

Diagnostic Test: - analysis for glucose and cholesterol in the capillary blood

express test

Diagnostic Test: - detection of microalbumuria

express test

Diagnostic Test: - heart ultrasound examination

Ultrasound examination with Lumify Handheld S4-1 Phased Array Ultrasound (Philips)

Diagnostic Test: - carotid artery ultrasound examination

Ultrasound examination with Lumify Handheld L12-4 Linear Array Ultrasound (Philips)

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

International Sites

Moscow 524901, Russia

Status

Address

National Medical Research Center for Therapy and Preventive Medicine

Moscow 524901, ,

Clinical Trial Finder