Application of Cognitive Training Based on Remind Strategy in Glioma Patients With Cognitive Impairment

Study Purpose

The purpose of this study is to form an interdisciplinary team to dynamically evaluate patient cognitive outcomes and develop an individualized cognitive training program for Chinese brain tumor patients

Recruitment Criteria

Accepts Healthy Volunteers Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms	No
Study Type An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies.	Interventional
Eligible Ages	18 Years - 70 Years
Gender	All

More Inclusion & Exclusion Criteria

Inclusion Criteria:

1. Conforming to the diagnostic criteria outlined in the "Chinese Clinical Guidelines for Diagnosis and Treatment of Central Nervous System Gliomas (2015)" ; 2. Patients diagnosed with brain gliomas through histopathological and/or cytological examination; 3. MoCA (Montreal Cognitive Assessment) score ≤ 26; 4. Karnofsky Performance Status (KPS) score ≥ 60, with no history of past illnesses; 5. Age ≥ 18 years; 6. Clear consciousness; 7. Willingness to participate and signed informed consent form.

Exclusion Criteria:

1. Diagnosed with neurological or psychiatric disorders within the past two years; 2. Impaired consciousness; 3. Accompanied by severe complications such as infections; 4. Nursing Delirium Screening Checklist (Nu-DESC) score ≥ 2; 5. Patients with changes in condition or requiring repeat surgery; 6. Patients with multiple intracranial tumors; 7. Inability to effectively complete the questionnaire or withdrawal during the study.

Trial Details

Trial ID: This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.	NCT06327048
Phase Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.	N/A
Lead Sponsor The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.	YuanYuan Ma
Principal Investigator The person who is responsible for the scientific and technical direction of the entire clinical study.	peifen ma, Master
Principal Investigator Affiliation	The Second Hospital of Lanzhou University
Agency Class Category of organization(s) involved as sponsor (and collaborator) supporting the trial.	Other
Overall Status	Recruiting
Countries	China
Conditions The disease, disorder, syndrome, illness, or injury that is being studied.	Glioma

Additional Details

Adult patients diagnosed with glioma who meet the inclusion criteria will be enrolled in this study. Patients admitted to Neurosurgery Ward 1 and Ward 2 will be assigned to the intervention group, while those admitted to Neurosurgery Ward 3 and Ward 4 will serve as the control group. The intervention group will receive cognitive rehabilitation training based on the Remind strategy in addition to standard rehabilitation care, whereas the control group will receive only standard rehabilitation care. Assessment of patients' cognitive function, quality of life, psychological status, and the effectiveness of cognitive training intervention will be conducted on the first day of admission, one day before discharge, and at the end of the intervention period.

Arms & Interventions

Arms

No Intervention: Control group

Routine rehabilitation nursing

Experimental: Intervention group

On the basis of routine rehabilitation nursing, individual cognitive rehabilitation training based on Remind strategy was given

Interventions

Other: - Individual cognitive rehabilitation training based on Remind strategy was given

This training educates and learns patients from the aspects of assessment of cognitive function and strategic compensation for the impact of cognitive impairment on patients, and then conducts attention, memory and executive function training and attention retraining based on patients' cognitive function to improve patients' cognitive function

Contact a Trial Team

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International Sites

Yuanyuanma, Lanzhou, Gansu, China

Status

Recruiting

Address

Yuanyuanma

Lanzhou, Gansu,

Site Contact

yuanyuan ma, Bachelor

[email protected]

15294126094

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