Predictive Factors for Medullary Thyroid Cancer Aggressiveness

Study Purpose

This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival.

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

No
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Observational
Eligible Ages 18 Years and Over
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

  • - Patients who underwent thyroidectomy for medullary thyroid cancer (total thyroidectomy, completion thyroidectomy) +/- central/lateral neck dissection.

Exclusion Criteria:

- Age < 18 years

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT06292988
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Aristotle University Of Thessaloniki
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Theodossis Papavramidis, Prof
Principal Investigator Affiliation 1st Propedeutic Department of Surgery, AHEPA University Hospital of Thessaloniki, Greece
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Other
Overall Status Not yet recruiting
Countries Austria, Belgium, Brazil, Bulgaria, China, Colombia, Croatia, France, Greece, India, Iraq, Italy, Jordan, Morocco, Poland, Serbia, Slovakia, Spain, Switzerland, Thailand, Turkey, Ukraine, United States, Vietnam
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Medullary Thyroid Cancer
Additional Details

This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival. The predictive factors included in this study are central and lateral compartment lymph node metastases as well as distant metastasis up to 1 year postoperatively, while biochemical predictors (meaning ratios such as lymphocyte to monocyte ratio etc and CEA and calcitonin drop levels) and histological predictors (such as nuclear atypia, amyloid, immunohistochemistry, desmoplasia) are included as secondary outcomes. In this study , patients >18 years old that underwent surgery for medullary thyroid cancer (total thyroidectomy, completion thyroidectomy) +/- central/lateral neck dissection) will be enrolled.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

Oregon City, Oregon

Status

Address

Oregon Health & Science University, Oregon

Oregon City, Oregon, 97239

Site Contact

James Lim

[email protected]

+306944536972

International Sites

Salzburg, Austria

Status

Address

Department of Surgery, Saint John of God Hospital, Salzburg, Austria

Salzburg, ,

Site Contact

Michael De Cilia

[email protected]

+306944536972

Saint Luc, University Clouvain, Belgium, Bruxelles, Belgium

Status

Address

Saint Luc, University Clouvain, Belgium

Bruxelles, ,

Site Contact

Antoine Buemi, Prof

[email protected]

+306944536972

Santa Cruz Do Sul, Brazil

Status

Address

Head and Neck Surgery Department, Hospital Ana Nery, Santa Cruz do Sul, Brazil

Santa Cruz Do Sul, ,

Site Contact

Fabio Muradas Girardi

[email protected]

+306944536972

Sofia, Bulgaria

Status

Address

University Clinic of Surgery, University Hospital "Lozenec"

Sofia, ,

Site Contact

Rumen Pandev

[email protected]

+306944536972

Chinese University of Hong Kong, Hong Kong, China

Status

Address

Chinese University of Hong Kong

Hong Kong, ,

Site Contact

Shirley Liu

[email protected]

+306944536972

Manizales, Colombia

Status

Address

Head and Neck Department Oncologos del Occidente, Universidad de Caldas, Manizales, Colombia

Manizales, ,

Site Contact

Andres Chalas

[email protected]

+306944536972

Zagreb, Croatia

Status

Address

the University Hospital Center Sestre milosrdnice, Zagreb, Croatia, Department of Otorhinolaryngology and Head and Neck Surgery

Zagreb, ,

Site Contact

Andro Kosec, Prof

[email protected]

+306944536972

Brest, France

Status

Address

Head and Neck Surgery, Brest University Hospital, Brest, France

Brest, ,

Site Contact

27. Jean-Christophe Leclere

[email protected]

+306944536972

Poitiers, France

Status

Address

The University Hospital of Poitiers, France

Poitiers, ,

Athens, Greece

Status

Address

Thyroid Surgery Clinic IKE, Athens, Greece

Athens, ,

Site Contact

Stavros Karakozis

[email protected]

+306944536972

Larissa, Greece

Status

Address

ENT Department University Hospital of Larissa

Larissa, ,

Site Contact

Jiannis Hajiioannou

[email protected]

+306944536972

Patra, Greece

Status

Address

Department of Surgery, General University Hospital of Patras

Patra, ,

Site Contact

Franko Mulita

[email protected]

+306944536972

Aristotle University of Thessaloniki, Thessaloníki, Greece

Status

Address

Aristotle University of Thessaloniki

Thessaloníki, ,

Gennimatas General Hospital, Thessaloníki, Greece

Status

Address

Gennimatas General Hospital

Thessaloníki, ,

Site Contact

Ioannis Koutelidakis

[email protected]

+306944536972

Bhubaneswar, India

Status

Address

Department of ENT-Head and Neck Surgery, All India Institute of Medical Sciences, Bhubaneswar

Bhubaneswar, ,

Site Contact

Kumar Parida Pradipta

[email protected]

+306944536972

Coimbatore, India

Status

Address

KMCH and KMCH Comprehensive Cancer Center

Coimbatore, ,

Site Contact

Manoj Dhiwakar

[email protected]

+306944536972

Madurai, India

Status

Address

Department of Endocrine and Breast Surgery at Sanjay Gandhi Post Graduate Institute of Medical Sciences

Madurai, ,

Site Contact

Sabaretnam Mayilvaganan

[email protected]

+306944536972

New Delhi, India

Status

Address

Department of Surgery, Maulana Azad Medical College & Lok Nayak Hospital

New Delhi, ,

Site Contact

Lovenish Bains

[email protected]

+306944536972

Vijayawada, India

Status

Address

Endocrine and Metabolic Surgery, Bhargav Endocrine Hospital, Vijayawada, India

Vijayawada, ,

Site Contact

Ramakanth Bhargav Panchangam

[email protected]

+306944536972

Erbil, Iraq

Status

Address

University of Sulaimani | UNIVSUL ,Department of Surgery, Kurdistan

Erbil, ,

Site Contact

Fahmi Hussein

[email protected]

+306944536972

Domodossola, Italy

Status

Address

ASL VCO - San Biagio Hospital - Domodossola (VB) - Italy

Domodossola, ,

Site Contact

Luigi Oragano

[email protected]

+306944536972

Genoa, Italy

Status

Address

Dipartimento di Scienze Chirurgiche (DISC), University of Genoa, Italy

Genoa, ,

Site Contact

Michele Minuto

[email protected]

+306944536972

Milan, Italy

Status

Address

Asst Santi Paolo e Carlo - Ospedale Polo Universitario San Paolo, Milan, Italy

Milan, ,

Site Contact

Loredana De Pasquale

[email protected]

+306944536972

Roma, Italy

Status

Address

UOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario A Gemelli IRCCS

Roma, ,

Site Contact

Marco Raffaelli

[email protected]

+306944536972

Trieste, Italy

Status

Address

Department of Medical and Surgical Sciences, University of Trieste, Cattinara Teaching Hospital, Trieste, Italy

Trieste, ,

Site Contact

Chiara Dobrinja

[email protected]

+306944536972

Verona, Italy

Status

Address

Department of Surgery and Oncology, Endocrine Surgery Unit, Verona University Hospital

Verona, ,

Site Contact

Giacomo DiFilippo

[email protected]

+306944536972

Hashemite University of Zarqa, Zarqa, Jordan

Status

Address

Hashemite University of Zarqa

Zarqa, ,

Site Contact

Sohail Bakkar, Prof

[email protected]

+306944536972

Marrakech, Morocco

Status

Address

Hepatobiliairy and endocrine surgery, Ibn Sina Hospital, Medical School of Medecine Rabat, Mohamed Vth University of Rabat Morocco

Marrakech, ,

Site Contact

Omar El Malki Hadj, Prof

[email protected]

+306944536972

Gdańsk, Poland

Status

Address

Division of General, Endocrine and Transplant Surgery, Medical University of Gdańsk

Gdańsk, ,

Site Contact

Andrzej Hellman, Prof

[email protected]

+306944536972

Belgrad, Serbia

Status

Address

Surgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Medical School, University of Belgrade

Belgrad, ,

Site Contact

Nada Santrac

[email protected]

+306944536972

Bratislava, Slovakia

Status

Address

Comenius University in Bratislava, Department of Paediatric Surgery, National Institute of Children's Diseases

Bratislava, ,

Site Contact

Petra Zahradníková, Prof

[email protected]

+306944536972

Bratislava, Slovakia

Status

Address

Department of oncological surgery, St. Elisabeth cancer Institute

Bratislava, ,

Site Contact

Robert Kralik

[email protected]

+306944536972

Hospital Clinic (Barcelona, Spain), Barcelona, Spain

Status

Address

Hospital Clinic (Barcelona, Spain)

Barcelona, ,

Site Contact

Aida Orois

[email protected]

+306944536972

Universitaria de Cordoba, Córdoba, Spain

Status

Address

Universitaria de Cordoba

Córdoba, ,

Site Contact

Constanza Ramacciotti

[email protected]

+306944536972

Hospital Regional de Málaga, Málaga, Spain

Status

Address

Hospital Regional de Málaga

Málaga, ,

Site Contact

Viyey Kishore Doulatram

[email protected]

+306944536972

Vigo, Spain

Status

Address

Department of General and Digestive Surgery, Division of Endocrine Surgery, Complexo Hospitalario Universitario de Vigo, Vigo, Spain

Vigo, ,

Site Contact

Angel Rivo Vazaquez

[email protected]

+306944536972

Bern University Hospital, Bern, Switzerland

Status

Address

Bern University Hospital

Bern, ,

Site Contact

Reto Kaderli, Prof

[email protected]

+306944536972

Geneva University Hospital, Geneva, Switzerland

Status

Address

Geneva University Hospital

Geneva, ,

Bangkok, Thailand

Status

Address

Division of Endocrinology and Metabolism Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok, Thailand

Bangkok, ,

Site Contact

Sriphrapradang Chutintorn

[email protected]

+306944536972

Ankara, Turkey

Status

Address

Ankara University Faculty of Medicine, Department of Endocrine Surgery

Ankara, ,

Site Contact

Volkan Cenc

[email protected]

+306944536972

Acibadem MAA University, Istanbul, Turkey

Status

Address

Acibadem MAA University

Istanbul, ,

Istanbul, Turkey

Status

Address

Cerrahpasa medical faculty endocrine surgery department

Istanbul, ,

Site Contact

Selen Soylu

[email protected]

+306944536972

Istanbul, Turkey

Status

Address

Department of Endocrin Pathology Unit, University of Health Sciences, Faculty of Medicine, Bakırköy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey

Istanbul, ,

Site Contact

Altinay Serdar

[email protected]

+306944536972

Kyiv, Ukraine

Status

Address

Endocrine surgeon-consultant, International medical center "CITIDOCTOR"

Kyiv, ,

Site Contact

Sergii Cherenko

[email protected]

+306944536972

Việt Trì, Vietnam

Status

Address

Department of Radiology, Thien Hanh Hospital, Buon Ma Thuot, Vietnam

Việt Trì, ,

Site Contact

Hoang Van Trung

[email protected]

+306944536972

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