Effects of Prostate Cancer on Brain Function

Study Purpose

To explore whether the patients with prostate cancer have functional changes in specific brain areas and changes in psychological and mental characteristics compared with the patients without prostate cancer.

Recruitment Criteria

Accepts Healthy Volunteers Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms	Yes
Study Type An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies.	Observational
Eligible Ages	18 Years - 80 Years
Gender	Male

More Inclusion & Exclusion Criteria

Inclusion Criteria:

1. Between the ages of 18 and 80. 2. Patients with prostate biopsy; 3. No history of other malignant tumors; 4. Exclude other malignant tumors; 5. Fully understand the clinical trial protocol and sign informed consent;

Exclusion Criteria:

1. magnetic resonance contraindications; 2. symptomatic acute or chronic inflammation of the prostate; 3. Patients with brain trauma or brain disease; 4. Patients who have died of other malignancies in the past or are currently suffering from other malignancies; 5. Patients judged by the investigator to be unfit to participate in the clinical trial;

Trial Details

Trial ID: This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.	NCT05737004
Phase Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.
Lead Sponsor The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.	Shanghai East Hospital
Principal Investigator The person who is responsible for the scientific and technical direction of the entire clinical study.	Haifeng Wang
Principal Investigator Affiliation	Shanghai East Hospital,Tongji University School of Medicine
Agency Class Category of organization(s) involved as sponsor (and collaborator) supporting the trial.	Other
Overall Status	Recruiting
Countries	China
Conditions The disease, disorder, syndrome, illness, or injury that is being studied.	Prostate Cancer

Additional Details

This study was intended to observe the functional changes of brain fMRI in patients with and without prostate cancer enrolled in the cohort of patients who planned to undergo prostate biopsy, in an attempt to discover specific brain region changes in patients with prostate cancer, and lay a foundation for further clarifying the relationship and mechanism between brain region function changes and prostate cancer.

Arms & Interventions

Arms

: Prostate cancer group

Prostate cancer was confirmed by biopsy, and fMRI examination 、Zung Self Rating Anxiety Scale and Beck Depression Inventory-II were performed in these patients within 1 week before biopsy .

: Non-Prostate cancer group

Non-Prostate cancer was confirmed by biopsy, and fMRI examination 、 Zung Self Rating Anxiety Scale and Beck Depression Inventory-II were performed in these patients within 1 week before biopsy .

Interventions

Diagnostic Test: - functional magnetic resonance imaging examination、Zung Self Rating Anxiety Scale and Beck Depression Inventory-II

fMRI examination 、Zung Self Rating Anxiety Scale and Beck Depression Inventory-II were performed in these patients within 1 week before biopsy .

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

International Sites

Shanghai, Shanghai, China

Status

Recruiting

Address

Shanghai East Hospital, Tongji University School of Medicine

Shanghai, Shanghai, 200120

Site Contact

Shuaidong Wang, Master

[email protected]

15102100859

Clinical Trial Finder