Clinical Trial Finder
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma
Study Purpose
This is an open-label brain PET/CT (positron emission tomography/computed tomography) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-BNOTA-PRGD2 in glioma patients. A single dose of nearly 111 MBq 68Ga-BNOTA-PRGD2 (≤40 µg BNOTA-PRGD2) will be intravenously injected into patients in suspicion of glioma. Visual and semiquantitative method will be used to assess the PET/CT images. Brain MRI with/without enhancement and 18F-FDG PET/CT will be performed for comparison. The postoperative pathology and integrin αvβ3 and CD34 immunohistochemical stains will also be used for correlation.
Recruitment Criteria
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Interventional |
Eligible Ages | 18 Years and Over |
Gender | All |
Trial Details
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT01801371 |
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
Early Phase 1 |
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Peking Union Medical College Hospital |
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Zhaohui Zhu, MD |
Principal Investigator Affiliation | Peking Union Medical College Hospital |
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
OtherOther |
Overall Status | Recruiting |
Countries | China |
The disease, disorder, syndrome, illness, or injury that is being studied. |
Glioma |
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