SwissNET - a Registry for Neuroendocrine Tumours in Switzerland

Study Purpose

Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are regarded as a fairly rare disease. They are derived from the neuroendocrine system of the gastrointestinal tract and the pancreas and share common clinical features. So far, there is still uncertainty about the cell biology and mechanistic regulation of these tumours. Therefore targeted treatment is limited and management challenging. Treatment options include surgery, medical and ablative therapy, and more recently peptide-receptor radionuclide therapy. In order to better understand the characteristics of GEP-NETs and to evaluate treatment strategies, the SwissNET registry aims at the collection of data from patients presenting with a GEP-NET in Switzerland. Data will be entered prospectively and anonymized in a specifically designed database after the patient has given informed consent. All hospitals and general practitioners are invited to report on patients with a GEP-NET diagnosis and to participate to the registry. Data will be evaluated within regular time frames, focussing on types of GEP-NETs, treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate), thereby contributing to the better understanding of these tumours.

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

No
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Observational
Eligible Ages N/A and Over
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

  • - Neuroendocrine tumor irrespective of primary tumor location.
  • - Diagnosis in Switzerland.
- Given informed consent

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT01039922
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Insel Gruppe AG, University Hospital Bern
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Aurel Perren, MD
Principal Investigator Affiliation Institute of Pathology, University of Bern, Bern
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Other, Industry
Overall Status Recruiting
Countries Switzerland
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Neuroendocrine Tumors, Carcinoid Tumor
Additional Details

Background.Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are generally classified as rare diseases. Little is known about their cell biology and their mechanistic regulation. During the last years, the incidence of GEP-NETs is continuously increasing worldwide. In parallel, novel treatment options are currently evaluated which may substantially improve prognosis of patients with NETs. Data on such tumours in Switzerland, however, is scarce and treatment strategies vary throughout the country. Objective.To systematically and prospectively collect clinical information of patients with GEP-NETs in Switzerland based on a histologically confirmed diagnosis. Methods.All NETs of both, gastrointestinal and pulmonary origin are included provided that patients have given informed consent. Data will be entered prospectively and anonymised in a specifically designed database. Contributing centres and general practitioners are visited by a study nurse, patient files are analysed and data is transferred to the database. In case of conflicting evidence, questions are resolved in collaboration with a review board of SwissNET. Evaluation of treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate) will take place within regular time frames.

Arms & Interventions

Arms

: 1

Patients with a histologically confirmed diagnosis of a neuroendocrine tumor irrespective of primary tumor location

Interventions

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

International Sites

Kantonsspital Aarau, Aarau 2661881, Switzerland

Status

Recruiting

Address

Kantonsspital Aarau

Aarau 2661881, ,

Spitalnetz Bern Aarberg, Aarberg 2661880, Switzerland

Status

Recruiting

Address

Spitalnetz Bern Aarberg

Aarberg 2661880, ,

Bezirksspital Affoltern, Affoltern am Albis 2661842, Switzerland

Status

Recruiting

Address

Bezirksspital Affoltern

Affoltern am Albis 2661842, ,

Kantonsspital Uri, Altdorf, Altdorf 2661780, Switzerland

Status

Recruiting

Address

Kantonsspital Uri, Altdorf

Altdorf 2661780, ,

St. Claraspital, Basel 2661604, Switzerland

Status

Recruiting

Address

St. Claraspital

Basel 2661604, ,

Universitätsspital Basel, Basel 2661604, Switzerland

Status

Recruiting

Address

Universitätsspital Basel

Basel 2661604, ,

Bellinzona 2661567, Switzerland

Status

Recruiting

Address

Istituto oncologico della Svizzera italiana

Bellinzona 2661567, ,

Bern 2661552, Switzerland

Status

Recruiting

Address

Div. of Endocrinology, Diabetes and Clinical Nutrition, Bern University Hospital

Bern 2661552, , 3010

Spital Tiefenau, Spitalnetz Bern, Bern 2661552, Switzerland

Status

Recruiting

Address

Spital Tiefenau, Spitalnetz Bern

Bern 2661552, ,

Zieglerspital Bern, Bern 2661552, Switzerland

Status

Recruiting

Address

Zieglerspital Bern

Bern 2661552, ,

Spitalzentrum Biel - Bienne, Biel 2661514, Switzerland

Status

Recruiting

Address

Spitalzentrum Biel - Bienne

Biel 2661514, ,

Kantonsspital Bruderholz, Bruderholz 8469026, Switzerland

Status

Recruiting

Address

Kantonsspital Bruderholz

Bruderholz 8469026, ,

Regionsspital Emmental, Burgdorf 2661321, Switzerland

Status

Recruiting

Address

Regionsspital Emmental

Burgdorf 2661321, ,

Kantonsspital Chur, Chur 2661169, Switzerland

Status

Recruiting

Address

Kantonsspital Chur

Chur 2661169, ,

Private practise Dr. Mannhart, Churwalden 2661167, Switzerland

Status

Recruiting

Address

Private practise Dr. Mannhart

Churwalden 2661167, ,

Hôpital du Jura, Delémont 2661035, Switzerland

Status

Recruiting

Address

Hôpital du Jura

Delémont 2661035, ,

Spital Dornach, Dornach 2660989, Switzerland

Status

Recruiting

Address

Spital Dornach

Dornach 2660989, ,

Regionalspital Einsiedeln, Einsiedeln 2660925, Switzerland

Status

Recruiting

Address

Regionalspital Einsiedeln

Einsiedeln 2660925, ,

Hôpitaux Universitaires de Genève, Geneva 2660646, Switzerland

Status

Recruiting

Address

Hôpitaux Universitaires de Genève

Geneva 2660646, ,

Spital Grabs, Grabs 2660543, Switzerland

Status

Recruiting

Address

Spital Grabs

Grabs 2660543, ,

See-Spital Horgen, Horgen 2660305, Switzerland

Status

Recruiting

Address

See-Spital Horgen

Horgen 2660305, ,

Spital Zimmerberg, Horgen 2660305, Switzerland

Status

Recruiting

Address

Spital Zimmerberg

Horgen 2660305, ,

Fmi Spital Interlaken, Interlaken 2660253, Switzerland

Status

Recruiting

Address

Fmi Spital Interlaken

Interlaken 2660253, ,

Spital Lachen, Lachen 2660075, Switzerland

Status

Recruiting

Address

Spital Lachen

Lachen 2660075, ,

Spital Region Oberaargau, Langenthal 2660034, Switzerland

Status

Recruiting

Address

Spital Region Oberaargau

Langenthal 2660034, ,

Kantonsspital Laufen, Laufen 2660001, Switzerland

Status

Recruiting

Address

Kantonsspital Laufen

Laufen 2660001, ,

Lausanne 2659994, Switzerland

Status

Recruiting

Address

Centre hospitalier universitaire vaudois, CHUV

Lausanne 2659994, ,

Kantonsspital Liestal, Liestal 2659891, Switzerland

Status

Recruiting

Address

Kantonsspital Liestal

Liestal 2659891, ,

Hirslandenklinik St. Anna, Lucerne 2659811, Switzerland

Status

Recruiting

Address

Hirslandenklinik St. Anna

Lucerne 2659811, ,

Kantonsspital Luzern, Lucerne 2659811, Switzerland

Status

Recruiting

Address

Kantonsspital Luzern

Lucerne 2659811, ,

Kantonsspital Sursee, Luzern, Lucerne 2659811, Switzerland

Status

Recruiting

Address

Kantonsspital Sursee, Luzern

Lucerne 2659811, ,

Kreisspital Männedorf, Männedorf 2659772, Switzerland

Status

Recruiting

Address

Kreisspital Männedorf

Männedorf 2659772, ,

Kantonsspital Münsterlingen, Münsterlingen 2659544, Switzerland

Status

Recruiting

Address

Kantonsspital Münsterlingen

Münsterlingen 2659544, ,

Kantonsspital Olten, Olten 2659297, Switzerland

Status

Recruiting

Address

Kantonsspital Olten

Olten 2659297, ,

Gesundheitszentrum Fricktal, Rheinfelden 2659060, Switzerland

Status

Recruiting

Address

Gesundheitszentrum Fricktal

Rheinfelden 2659060, ,

Kantonsspital St. Gallen, Sankt Gallen 2658822, Switzerland

Status

Recruiting

Address

Kantonsspital St. Gallen

Sankt Gallen 2658822, ,

Kantonsspital Obwalden, Sarnen 2658786, Switzerland

Status

Recruiting

Address

Kantonsspital Obwalden

Sarnen 2658786, ,

Spital Limmattal, Schlieren 2658724, Switzerland

Status

Recruiting

Address

Spital Limmattal

Schlieren 2658724, ,

Spital Schwyz, Schwyz 2658665, Switzerland

Status

Recruiting

Address

Spital Schwyz

Schwyz 2658665, ,

Privatpraxis Dr. H.J. Poths, Seuzach Dorf 6295545, Switzerland

Status

Recruiting

Address

Privatpraxis Dr. H.J. Poths

Seuzach Dorf 6295545, ,

Centre hospitalier du centre du Valais, Sion 2658576, Switzerland

Status

Recruiting

Address

Centre hospitalier du centre du Valais

Sion 2658576, ,

Bürgerspital Solothurn, Solothurn 2658564, Switzerland

Status

Recruiting

Address

Bürgerspital Solothurn

Solothurn 2658564, ,

Kantonsspital Nidwalden, Stans 2658504, Switzerland

Status

Recruiting

Address

Kantonsspital Nidwalden

Stans 2658504, ,

Thun Spital STS AG, Thun 2658377, Switzerland

Status

Recruiting

Address

Thun Spital STS AG

Thun 2658377, ,

Spital Uster, Uster 2658216, Switzerland

Status

Recruiting

Address

Spital Uster

Uster 2658216, ,

Regionalspital Visp, Visp 2658112, Switzerland

Status

Recruiting

Address

Regionalspital Visp

Visp 2658112, ,

Kantonsspital Winterthur, Winterthur 2657970, Switzerland

Status

Recruiting

Address

Kantonsspital Winterthur

Winterthur 2657970, ,

Kantonsspital Wolhusen, Wolhusen 2657956, Switzerland

Status

Recruiting

Address

Kantonsspital Wolhusen

Wolhusen 2657956, ,

Spital Zollikerberg, Zollikerberg 6293731, Switzerland

Status

Recruiting

Address

Spital Zollikerberg

Zollikerberg 6293731, ,

Zuger Kantonsspital AG, Zug 2657908, Switzerland

Status

Recruiting

Address

Zuger Kantonsspital AG

Zug 2657908, ,

Pathologie Medica Zürich, Zurich 2657896, Switzerland

Status

Recruiting

Address

Pathologie Medica Zürich

Zurich 2657896, ,

Stadtspital Triemli, Zurich 2657896, Switzerland

Status

Recruiting

Address

Stadtspital Triemli

Zurich 2657896, ,

Stadtspital Waid, Zurich 2657896, Switzerland

Status

Recruiting

Address

Stadtspital Waid

Zurich 2657896, ,

Universitätsspital Zürich, Zurich 2657896, Switzerland

Status

Recruiting

Address

Universitätsspital Zürich

Zurich 2657896, ,

STS AG Spital Zweisimmen, Zweisimmen 2657887, Switzerland

Status

Recruiting

Address

STS AG Spital Zweisimmen

Zweisimmen 2657887, ,

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