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Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant temozolomide versus radiation with adjuvant PCV is more effective in treating anaplastic glioma or low grade glioma.
Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Interventional |
Eligible Ages | 18 Years and Over |
Gender | All |
Pre-Registration
Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT00887146 |
Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
Phase 3 |
Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Alliance for Clinical Trials in Oncology |
Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Kurt Jaeckle, MD |
Principal Investigator Affiliation | Mayo Clinic |
Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
Other, NIH |
Overall Status | Recruiting |
Countries | Austria, Belgium, Canada, France, Netherlands, United States |
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Brain and Central Nervous System Tumors |
Study Website: | View Trial Website |
This study will be a randomized phase III for patients with newly diagnosed co-deleted 1p/19q anaplastic glioma or high risk low grade glioma. The trial will only enroll patients with 1p/19q co-deletion. This study includes two arms as described in the "Arms" section. A dynamic allocation procedure will be used to allocate an equal number of patients to different arms (Arms A:B = 1:1). This procedure will balance the marginal distributions of the stratification factors among arms. The stratification factors that will be used are cooperative groups (EORTC vs.#46; all North American groups), age (≤ 50 vs.#46; > 50), performance score (ECOG 0-1 vs.#46; 2), and tumor grade (anaplastic glioma vs.#46; low grade glioma). The primary goal is to determine whether patients who receive radiotherapy with concomitant temozolomide (TMZ) followed by adjuvant temozolomide (RT + TMZ --> TMZ) (Arm B) have a marginally better progression free survival (PFS) as compared with patients who receive radiotherapy followed by PCV chemotherapy (RT --> PCV)(Arm A). Secondary Goals: 1. Time to Progression
Experimental: Arm A (RT, procarbazine, lomustine, vincristine)
Patients undergo 3D-CRT or IMRT on days 1-5 for 5-7 weeks. Patients also receive procarbazine hydrochloride PO on days 8-21, lomustine PO on day 1 and vincristine sulfate IV on days 8 and 29 of courses 3-8. Treatment repeats every 6-7 weeks for up to 6 courses in the absence of disease progression or unacceptable toxicity.
Experimental: Arm B (RT, temozolomide)
Patients undergo RT as in arm I and receive temozolomide PO QD on days 1-5 for 5-7 weeks. Beginning 4 weeks after completion of concurrent chemoradiotherapy, patients receive adjuvant temozolomide PO QD days 1-5. Treatment with adjuvant temozolomide repeats every 4 weeks for 6-12 courses in the absence of disease progression and unacceptable toxicity.
Drug: - concomitant temozolomide (TMZ)
75 mg/m^2, orally daily
Radiation: - radiotherapy
Drug: - procarbazine
Days 8-21: 60 mg/m^2 orally
Drug: - adjuvant temozolomide (TMZ)
150 or 200 mg/m^2 orally
Drug: - CCNU
Day 1: 110 mg/m^2 orally
Drug: - vincristine
Days 8 and 29: 1.4 mg/m^2 IV
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Status
Recruiting
Address
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
Status
Suspended
Address
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, 98508
Site Contact
Status
Suspended
Address
Alaska Oncology and Hematology LLC
Anchorage, Alaska, 99508
Site Contact
Status
Suspended
Address
Alaska Women's Cancer Care
Anchorage, Alaska, 99508
Site Contact
Status
Suspended
Address
Anchorage Oncology Centre
Anchorage, Alaska, 99508
Site Contact
Status
Recruiting
Address
Providence Alaska Medical Center
Anchorage, Alaska, 99508
Status
Recruiting
Address
Saint Joseph's Hospital and Medical Center
Phoenix, Arizona, 85013
Status
Suspended
Address
Arizona Oncology-Deer Valley Center
Phoenix, Arizona, 85027
Site Contact
Status
Suspended
Address
Arizona Oncology Services Foundation
Scottsdale, Arizona, 85260
Site Contact
Status
Recruiting
Address
Kaiser Permanente-Anaheim
Anaheim, California, 92806
Status
Suspended
Address
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California, 95603
Site Contact
Status
Suspended
Address
Mills-Peninsula Medical Center
Burlingame, California, 94010
Site Contact
Status
Suspended
Address
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park, California, 95682
Site Contact
Status
Active, not recruiting
Address
Community Cancer Institute
Clovis, California, 93611
Site Contact
Status
Active, not recruiting
Address
University Oncology Associates
Clovis, California, 93611
Site Contact
Status
Recruiting
Address
UC San Diego Moores Cancer Center
La Jolla, California, 92093
Status
Recruiting
Address
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, 90027
Status
Active, not recruiting
Address
Cedars Sinai Medical Center
Los Angeles, California, 90048
Site Contact
Status
Suspended
Address
Memorial Medical Center
Modesto, California, 95355
Site Contact
Status
Suspended
Address
Kaiser Permanente Oakland-Broadway
Oakland, California, 94611
Site Contact
Status
Recruiting
Address
Kaiser Permanente-Ontario
Ontario, California, 91761
Status
Recruiting
Address
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868
Status
Recruiting
Address
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, California, 95661
Status
Suspended
Address
Sutter Roseville Medical Center
Roseville, California, 95661
Site Contact
Status
Recruiting
Address
Sutter Medical Center Sacramento
Sacramento, California, 95816
Status
Recruiting
Address
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
Status
Suspended
Address
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, 95051
Site Contact
Status
Suspended
Address
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080
Site Contact
Status
Suspended
Address
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville, California, 95687
Site Contact
Status
Suspended
Address
Sutter Solano Medical Center/Cancer Center
Vallejo, California, 94589
Site Contact
Status
Active, not recruiting
Address
The Medical Center of Aurora
Aurora, Colorado, 80012
Site Contact
Status
Active, not recruiting
Address
UCHealth University of Colorado Hospital
Aurora, Colorado, 80045
Site Contact
Status
Recruiting
Address
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907
Status
Recruiting
Address
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, 80907
Status
Active, not recruiting
Address
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, 80909
Site Contact
Status
Recruiting
Address
Saint Francis Cancer Center
Colorado Springs, Colorado, 80923
Status
Recruiting
Address
Porter Adventist Hospital
Denver, Colorado, 80210
Status
Recruiting
Address
Littleton Adventist Hospital
Littleton, Colorado, 80122
Status
Recruiting
Address
Longmont United Hospital
Longmont, Colorado, 80501
Status
Suspended
Address
Banner McKee Medical Center
Loveland, Colorado, 80539
Site Contact
Status
Recruiting
Address
Parker Adventist Hospital
Parker, Colorado, 80138
Status
Recruiting
Address
Saint Mary Corwin Medical Center
Pueblo, Colorado, 81004
Status
Recruiting
Address
Yale University
New Haven, Connecticut, 06520
Status
Recruiting
Address
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, 06611
Status
Recruiting
Address
Sibley Memorial Hospital
Washington, District of Columbia, 20016
Status
Recruiting
Address
Boca Raton Regional Hospital
Boca Raton, Florida, 33486
Status
Recruiting
Address
University of Florida Health Science Center - Gainesville
Gainesville, Florida, 32610
Status
Suspended
Address
Baptist MD Anderson Cancer Center
Jacksonville, Florida, 32207
Site Contact
Status
Recruiting
Address
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980
Status
Recruiting
Address
AdventHealth Orlando
Orlando, Florida, 32803
Status
Recruiting
Address
Orlando Health Cancer Institute
Orlando, Florida, 32806
Status
Suspended
Address
Emory Proton Therapy Center
Atlanta, Georgia, 30308
Site Contact
Status
Suspended
Address
Emory University Hospital Midtown
Atlanta, Georgia, 30308
Site Contact
Status
Active, not recruiting
Address
Piedmont Hospital
Atlanta, Georgia, 30309
Site Contact
Status
Recruiting
Address
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322
Status
Recruiting
Address
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, 83605
Status
Recruiting
Address
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, 83687
Status
Suspended
Address
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, 83854
Site Contact
Status
Recruiting
Address
Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704
Status
Recruiting
Address
Illinois CancerCare-Canton
Canton, Illinois, 61520
Status
Recruiting
Address
Illinois CancerCare-Carthage
Carthage, Illinois, 62321
Status
Suspended
Address
Centralia Oncology Clinic
Centralia, Illinois, 62801
Site Contact
Status
Active, not recruiting
Address
Northwestern University
Chicago, Illinois, 60611
Site Contact
Status
Recruiting
Address
University of Illinois
Chicago, Illinois, 60612
Status
Suspended
Address
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
Site Contact
Status
Suspended
Address
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526
Site Contact
Status
Recruiting
Address
Decatur Memorial Hospital
Decatur, Illinois, 62526
Status
Recruiting
Address
Crossroads Cancer Center
Effingham, Illinois, 62401
Status
Recruiting
Address
Illinois CancerCare-Eureka
Eureka, Illinois, 61530
Status
Recruiting
Address
Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401
Status
Suspended
Address
Western Illinois Cancer Treatment Center
Galesburg, Illinois, 61401
Site Contact
Status
Recruiting
Address
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443
Status
Active, not recruiting
Address
AMITA Health Adventist Medical Center
La Grange, Illinois, 60525
Site Contact
Status
Recruiting
Address
Illinois CancerCare-Macomb
Macomb, Illinois, 61455
Status
Recruiting
Address
Loyola University Medical Center
Maywood, Illinois, 60153
Status
Suspended
Address
Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269
Site Contact
Status
Recruiting
Address
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350
Status
Active, not recruiting
Address
Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
Site Contact
Status
Recruiting
Address
Illinois CancerCare-Pekin
Pekin, Illinois, 61554
Status
Recruiting
Address
OSF Saint Francis Radiation Oncology at Pekin
Pekin, Illinois, 61554
Status
Recruiting
Address
Illinois CancerCare-Peoria
Peoria, Illinois, 61615
Status
Recruiting
Address
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois, 61615
Status
Suspended
Address
Methodist Medical Center of Illinois
Peoria, Illinois, 61636
Site Contact
Status
Recruiting
Address
OSF Saint Francis Medical Center
Peoria, Illinois, 61637
Status
Recruiting
Address
Illinois CancerCare-Peru
Peru, Illinois, 61354
Status
Recruiting
Address
Illinois CancerCare-Princeton
Princeton, Illinois, 61356
Status
Recruiting
Address
Memorial Medical Center
Springfield, Illinois, 62781
Status
Active, not recruiting
Address
Parkview Hospital Randallia
Fort Wayne, Indiana, 46805
Site Contact
Status
Active, not recruiting
Address
Parkview Regional Medical Center
Fort Wayne, Indiana, 46845
Site Contact
Status
Suspended
Address
Memorial Regional Cancer Center Day Road
Mishawaka, Indiana, 46545
Site Contact
Status
Suspended
Address
Memorial Hospital of South Bend
South Bend, Indiana, 46601
Site Contact
Status
Active, not recruiting
Address
McFarland Clinic - Ames
Ames, Iowa, 50010
Site Contact
Status
Recruiting
Address
Mercy Cancer Center-West Lakes
Clive, Iowa, 50325
Status
Suspended
Address
Mission Cancer and Blood - West Des Moines
Clive, Iowa, 50325
Site Contact
Status
Recruiting
Address
Greater Regional Medical Center
Creston, Iowa, 50801
Status
Recruiting
Address
Iowa Methodist Medical Center
Des Moines, Iowa, 50309
Status
Suspended
Address
Mission Cancer and Blood - Des Moines
Des Moines, Iowa, 50309
Site Contact
Status
Suspended
Address
Broadlawns Medical Center
Des Moines, Iowa, 50314
Site Contact
Status
Recruiting
Address
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314
Status
Suspended
Address
Mission Cancer and Blood - Laurel
Des Moines, Iowa, 50314
Site Contact
Status
Suspended
Address
Methodist West Hospital
West Des Moines, Iowa, 50266-7700
Site Contact
Status
Suspended
Address
Mercy Medical Center-West Lakes
West Des Moines, Iowa, 50266
Site Contact
Status
Recruiting
Address
University of Kansas Cancer Center
Kansas City, Kansas, 66160
Status
Recruiting
Address
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, 66210
Status
Recruiting
Address
University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas, 66211
Status
Recruiting
Address
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, 66205
Status
Recruiting
Address
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536
Status
Recruiting
Address
Norton Hospital Pavilion and Medical Campus
Louisville, Kentucky, 40202
Status
Recruiting
Address
Norton Brownsboro Hospital and Medical Campus
Louisville, Kentucky, 40241
Status
Recruiting
Address
West Jefferson Medical Center
Marrero, Louisiana, 70072
Status
Active, not recruiting
Address
Maine Medical Center-Bramhall Campus
Portland, Maine, 04102
Site Contact
Status
Recruiting
Address
Maine Medical Center- Scarborough Campus
Scarborough, Maine, 04074
Status
Suspended
Address
Maine Medical Partners Neurology
Scarborough, Maine, 04074
Site Contact
Status
Suspended
Address
Maine Medical Partners - South Portland
South Portland, Maine, 04106
Site Contact
Status
Recruiting
Address
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287
Status
Recruiting
Address
Walter Reed National Military Medical Center
Bethesda, Maryland, 20889-5600
Status
Recruiting
Address
Cancer Trials Support Unit
Rockville, Maryland, 20850-2062
Status
Suspended
Address
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114
Site Contact
Status
Active, not recruiting
Address
Bixby Medical Center
Adrian, Michigan, 49221
Site Contact
Status
Recruiting
Address
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109
Status
Active, not recruiting
Address
Henry Ford Hospital
Detroit, Michigan, 48202
Site Contact
Status
Recruiting
Address
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan, 49503
Status
Suspended
Address
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, 49503
Site Contact
Status
Recruiting
Address
West Michigan Cancer Center
Kalamazoo, Michigan, 49007
Status
Active, not recruiting
Address
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, 48073
Site Contact
Status
Recruiting
Address
Munson Medical Center
Traverse City, Michigan, 49684
Status
Active, not recruiting
Address
William Beaumont Hospital - Troy
Troy, Michigan, 48085
Site Contact
Status
Recruiting
Address
University of Michigan Health - West
Wyoming, Michigan, 49519
Status
Suspended
Address
Fairview Ridges Hospital
Burnsville, Minnesota, 55337
Site Contact
Status
Recruiting
Address
Mercy Hospital
Coon Rapids, Minnesota, 55433
Status
Suspended
Address
Essentia Health Cancer Center
Duluth, Minnesota, 55805
Site Contact
Status
Recruiting
Address
Miller-Dwan Hospital
Duluth, Minnesota, 55805
Status
Recruiting
Address
Fairview Southdale Hospital
Edina, Minnesota, 55435
Status
Active, not recruiting
Address
Unity Hospital
Fridley, Minnesota, 55432
Site Contact
Status
Recruiting
Address
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109
Status
Recruiting
Address
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109
Status
Recruiting
Address
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
Status
Recruiting
Address
Hennepin County Medical Center
Minneapolis, Minnesota, 55415
Status
Recruiting
Address
North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422
Status
Recruiting
Address
Mayo Clinic in Rochester
Rochester, Minnesota, 55905
Status
Recruiting
Address
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, 56303
Status
Recruiting
Address
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416
Status
Recruiting
Address
Regions Hospital
Saint Paul, Minnesota, 55101
Status
Recruiting
Address
United Hospital
Saint Paul, Minnesota, 55102
Status
Suspended
Address
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379
Site Contact
Status
Recruiting
Address
Ridgeview Medical Center
Waconia, Minnesota, 55387
Status
Suspended
Address
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125
Site Contact
Status
Recruiting
Address
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703
Status
Recruiting
Address
MU Health - University Hospital/Ellis Fischel Cancer Center
Columbia, Missouri, 65212
Status
Recruiting
Address
University of Kansas Cancer Center - North
Kansas City, Missouri, 64154
Status
Recruiting
Address
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, 64064
Status
Recruiting
Address
University of Kansas Cancer Center at North Kansas City Hospital
North Kansas City, Missouri, 64116
Status
Recruiting
Address
Washington University School of Medicine
Saint Louis, Missouri, 63110
Status
Recruiting
Address
Mercy Hospital Saint Louis
Saint Louis, Missouri, 63141
Status
Recruiting
Address
Billings Clinic Cancer Center
Billings, Montana, 59101
Status
Suspended
Address
Saint Vincent Healthcare
Billings, Montana, 59101
Site Contact
Status
Recruiting
Address
Benefis Sletten Cancer Institute
Great Falls, Montana, 59405
Status
Recruiting
Address
Great Falls Clinic
Great Falls, Montana, 59405
Status
Suspended
Address
Nebraska Cancer Specialists/Oncology Hematology West PC
Grand Island, Nebraska, 68803
Site Contact
Status
Suspended
Address
CHI Health Good Samaritan
Kearney, Nebraska, 68847
Site Contact
Status
Suspended
Address
Nebraska Hematology and Oncology
Lincoln, Nebraska, 68506
Site Contact
Status
Suspended
Address
Cancer Partners of Nebraska
Lincoln, Nebraska, 68516
Site Contact
Status
Recruiting
Address
Missouri Valley Cancer Consortium
Omaha, Nebraska, 68106
Status
Suspended
Address
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122
Site Contact
Status
Recruiting
Address
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124
Status
Suspended
Address
Nebraska Cancer Specialists - Omaha
Omaha, Nebraska, 68124
Site Contact
Status
Suspended
Address
Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130
Site Contact
Status
Recruiting
Address
University of Nebraska Medical Center
Omaha, Nebraska, 68198
Status
Suspended
Address
Midlands Community Hospital
Papillion, Nebraska, 68046
Site Contact
Status
Suspended
Address
Regional West Medical Center Cancer Center
Scottsbluff, Nebraska, 69361
Site Contact
Status
Recruiting
Address
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada, 89106
Status
Suspended
Address
GenesisCare USA - Las Vegas
Las Vegas, Nevada, 89109
Site Contact
Status
Recruiting
Address
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada, 89119
Status
Suspended
Address
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, 89148
Site Contact
Status
Recruiting
Address
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada, 89169
Status
Recruiting
Address
Renown Regional Medical Center
Reno, Nevada, 89502
Status
Recruiting
Address
Saint Mary's Regional Medical Center
Reno, Nevada, 89503
Status
Suspended
Address
Radiation Oncology Associates
Reno, Nevada, 89509
Site Contact
Status
Recruiting
Address
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756
Status
Recruiting
Address
Jersey Shore Medical Center
Neptune, New Jersey, 07753
Status
Active, not recruiting
Address
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
New Brunswick, New Jersey, 08903
Site Contact
Status
Active, not recruiting
Address
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903
Site Contact
Status
Active, not recruiting
Address
Overlook Hospital
Summit, New Jersey, 07902
Site Contact
Status
Recruiting
Address
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106
Status
Active, not recruiting
Address
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York, 11215
Site Contact
Status
Active, not recruiting
Address
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
Site Contact
Status
Recruiting
Address
University of Rochester
Rochester, New York, 14642
Status
Active, not recruiting
Address
State University of New York Upstate Medical University
Syracuse, New York, 13210
Site Contact
Status
Active, not recruiting
Address
Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157
Site Contact
Status
Recruiting
Address
Altru Cancer Center
Grand Forks, North Dakota, 58201
Status
Active, not recruiting
Address
Case Western Reserve University
Cleveland, Ohio, 44106
Site Contact
Status
Suspended
Address
MetroHealth Medical Center
Cleveland, Ohio, 44109
Site Contact
Status
Suspended
Address
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
Site Contact
Status
Recruiting
Address
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
Status
Recruiting
Address
Riverside Methodist Hospital
Columbus, Ohio, 43214
Status
Recruiting
Address
The Mark H Zangmeister Center
Columbus, Ohio, 43219
Status
Suspended
Address
Mount Carmel Health Center West
Columbus, Ohio, 43222
Site Contact
Status
Recruiting
Address
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, 44124
Status
Recruiting
Address
ProMedica Flower Hospital
Sylvania, Ohio, 43560
Status
Active, not recruiting
Address
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio, 44691
Site Contact
Status
Recruiting
Address
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
Status
Recruiting
Address
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma, 74146
Status
Suspended
Address
Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015
Site Contact
Status
Active, not recruiting
Address
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030
Site Contact
Status
Active, not recruiting
Address
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210
Site Contact
Status
Suspended
Address
Providence Portland Medical Center
Portland, Oregon, 97213
Site Contact
Status
Suspended
Address
Providence Saint Vincent Medical Center
Portland, Oregon, 97225
Site Contact
Status
Active, not recruiting
Address
Jefferson Abington Hospital
Abington, Pennsylvania, 19001
Site Contact
Status
Suspended
Address
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
Site Contact
Status
Recruiting
Address
Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania, 18015
Status
Active, not recruiting
Address
Geisinger Medical Center
Danville, Pennsylvania, 17822
Site Contact
Status
Recruiting
Address
Saint Luke's Hospital-Anderson Campus
Easton, Pennsylvania, 18045
Status
Recruiting
Address
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
Status
Active, not recruiting
Address
Temple University Hospital
Philadelphia, Pennsylvania, 19140
Site Contact
Status
Active, not recruiting
Address
Allegheny General Hospital
Pittsburgh, Pennsylvania, 15212
Site Contact
Status
Active, not recruiting
Address
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232
Site Contact
Status
Recruiting
Address
Reading Hospital
West Reading, Pennsylvania, 19611
Status
Active, not recruiting
Address
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, 18711
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina, 29316
Site Contact
Status
Recruiting
Address
Medical University of South Carolina
Charleston, South Carolina, 29425
Status
Suspended
Address
Greenville Health System Cancer Institute-Andrews
Greenville, South Carolina, 29601
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina, 29605
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, 29605
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, 29615
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Greer
Greer, South Carolina, 29650
Site Contact
Status
Active, not recruiting
Address
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, 29672
Site Contact
Status
Suspended
Address
Spartanburg Medical Center
Spartanburg, South Carolina, 29303
Site Contact
Status
Recruiting
Address
Rapid City Regional Hospital
Rapid City, South Dakota, 57701
Status
Active, not recruiting
Address
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232
Site Contact
Status
Recruiting
Address
Parkland Memorial Hospital
Dallas, Texas, 75235
Status
Recruiting
Address
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
Status
Recruiting
Address
University of Texas Medical Branch
Galveston, Texas, 77555-0565
Status
Suspended
Address
UTMB Cancer Center at Victory Lakes
League City, Texas, 77573
Site Contact
Status
Recruiting
Address
Sandra L Maxwell Cancer Center
Cedar City, Utah, 84720
Status
Recruiting
Address
Intermountain Medical Center
Murray, Utah, 84107
Status
Recruiting
Address
Utah Valley Regional Medical Center
Provo, Utah, 84604
Status
Recruiting
Address
Saint George Regional Medical Center
Saint George, Utah, 84770
Status
Suspended
Address
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, 84106
Site Contact
Status
Active, not recruiting
Address
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
Site Contact
Status
Recruiting
Address
Dartmouth Cancer Center - North
Saint Johnsbury, Vermont, 05819
Status
Recruiting
Address
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
Status
Recruiting
Address
VCU Community Memorial Health Center
South Hill, Virginia, 23970
Status
Recruiting
Address
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225
Status
Suspended
Address
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336
Site Contact
Status
Suspended
Address
Tri-Cities Cancer Center
Kennewick, Washington, 99336
Site Contact
Status
Recruiting
Address
Skagit Regional Health Cancer Care Center
Mount Vernon, Washington, 98274
Status
Active, not recruiting
Address
Skagit Valley Hospital
Mount Vernon, Washington, 98274
Site Contact
Status
Active, not recruiting
Address
Virginia Mason Medical Center
Seattle, Washington, 98101
Site Contact
Status
Active, not recruiting
Address
FHCC South Lake Union
Seattle, Washington, 98109
Site Contact
Status
Active, not recruiting
Address
Fred Hutchinson Cancer Center
Seattle, Washington, 98109
Site Contact
Status
Suspended
Address
University of Washington Medical Center - Montlake
Seattle, Washington, 98195
Site Contact
Status
Recruiting
Address
PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664
Status
Active, not recruiting
Address
West Virginia University Healthcare
Morgantown, West Virginia, 26506
Site Contact
Status
Recruiting
Address
Northwest Wisconsin Cancer Center
Ashland, Wisconsin, 54806
Status
Recruiting
Address
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, 54601
Status
Active, not recruiting
Address
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
Site Contact
Status
Recruiting
Address
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
Status
Recruiting
Address
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, 53149
Status
Recruiting
Address
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, 53066
Status
Suspended
Address
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188
Site Contact
Status
Recruiting
Address
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, 53188
Status
Recruiting
Address
Medical University Vienna
Vienna, , A-1090
Status
Recruiting
Address
Alegemeen Ziekenhuis Middelheim
Antwerpen, , 2020
Status
Recruiting
Address
Tom Baker Cancer Centre
Calgary, Alberta, T2N 4N2
Status
Active, not recruiting
Address
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2
Site Contact
Status
Recruiting
Address
BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6
Status
Recruiting
Address
CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9
Status
Recruiting
Address
London Regional Cancer Program
London, Ontario, N6A 4L6
Status
Suspended
Address
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, K1H 8L6
Site Contact
Status
Suspended
Address
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5
Site Contact
Status
Suspended
Address
University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Site Contact
Status
Suspended
Address
CHUM - Hopital Notre-Dame
Montreal, Quebec, H2L 4M1
Site Contact
Status
Recruiting
Address
CHUM - Centre Hospitalier de l'Universite de Montreal
Montreal, Quebec, H2X 3E4
Status
Suspended
Address
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Site Contact
Status
Recruiting
Address
Centre Leon Berard
Lyon, , 69373
Status
Recruiting
Address
Centre Antoine Lacassagne
Nice, , 06189
Status
Recruiting
Address
Gustave Roussy
Villejuif, , 94805
Status
Recruiting
Address
Academ Zienkenhuis Bij De University
Amsterdam, , 1007 MB
Status
Recruiting
Address
University Medical Center Groningen
Groningen, , 9700 GZ
Status
Recruiting
Address
Maastro Clinic-Maastricht Radiation Oncology
Maastricht, , 6229 NA
Status
Recruiting
Address
Erasmus University Medical Center
Rotterdam, , 3015 CE