Clinical Trial Finder

Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma

Study Purpose

This phase II trial studies how well vemurafenib and cobimetinib work in treating patients with BRAF V600E mutation positive craniopharyngioma. Vemurafenib and cobimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Recruitment Criteria

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

Accepts Healthy Volunteers
No

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Study Type
Interventional
Eligible Ages 18 Years and Over
Gender All
More Inclusion & Exclusion Criteria

  • - Pre-registration: Patients must have local diagnosis of papillary craniopharyngioma and have tissue slides available for submission to central pathology review; central pathology review will include immunohistochemistry (IHC) testing for BRAF V600E mutation (VE1 clone) and beta-catenin IHC (membranous, non-nuclear pattern) if needed to confirm diagnosis of papillary craniopharyngioma - Histologically proven papillary craniopharyngioma as documented by central pathology review with positive BRAF V600E mutation by IHC - Measurable disease and/or non-measurable disease - Measurable disease, defined as bidimensionally measurable lesions with clearly defined margins by magnetic resonance imaging (MRI) scans, with a minimum diameter of 10 mm in both dimensions - Progressive disease required in cohort B, defined as an increase in the bidirectional area by 25% within the past 13 months after surgery or radiation; progressive or recurrent disease is not required in cohort A, but is allowed provided it is a new diagnosis and patient has not received prior treatment.
- Prior treatment - Cohort A: No prior therapy received other than surgery - Cohort B: Prior radiation therapy required (any type of prior radiation is allowed) - For patients treated with external beam radiation therapy, interstitial brachytherapy or radiosurgery, an interval of >= 3 months must have elapsed from completion of radiation therapy to registration - Recovered to Common Terminology Criteria for Adverse Events (CTCAE) grade 1 or less toxicity attributed to radiation with exception of alopecia, fatigue - For patients enrolling on Cohort A or Cohort B: - For patients treated with surgery, an interval of >= 21 days must have elapsed prior to registration - No prior treatment with BRAF or MEK inhibitors - Steroid dosing stable for at least 4 days prior to registration - Not pregnant and not nursing; for women of childbearing potential only, a negative pregnancy test done =< 7 days prior to registration is required - ECOG performance status =< 2 - Comorbid conditions - No evidence of active bleeding, bleeding diathesis, or hemoptysis (>= 1/2 teaspoon of red blood) =< 8 weeks prior to registration - No evidence of intracranial hemorrhage =< 4 weeks prior to registration - Patients who have experienced thromboembolic event within 6 months prior to registration must be on stable therapeutic anticoagulation for at least 4 weeks prior to registration - No symptomatic congestive heart failure (New York Heart Association class II, III, or IV) within 6 months prior to registration - No current unstable angina or uncontrolled arrhythmia - No uncontrolled hypertension at time of registration (blood pressure [BP] > 150/95 despite antihypertensive therapy) - No known history of prolonged QT syndrome - No known history of ventricular arrhythmia within 6 months of registration - No known history of uveitis or iritis =< 4 weeks prior to registration - No known history of or evidence of retinal pathology that is considered a risk factor for neurosensory retinal detachment, retinal vein occlusion (RVO), or neovascular macular degeneration within 12 months of registration - No known history of chronic lung disease - Concomitant medications - Chronic concomitant treatment with strong CYP3A4 inducers or CYP3A4 inhibitors is not allowed; patients must discontinue the drug at least 14 days prior to study registration - Chronic concomitant treatment with CYP1A2 substrate is not allowed; patients must discontinue the drug at least 14 days prior to study registration - Absolute neutrophil count >= 1500/mm^3 - Platelets >= 100,000/mm^3 - Creatinine =< 1.5 mg/dL OR creatinine clearance >= 45mL/min - Bilirubin =< 1.5 upper limit of normal (ULN) - Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 ULN

Trial Details

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

Trial ID:
NCT03224767

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Phase
Phase 2

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Lead Sponsor
Alliance for Clinical Trials in Oncology

The person who is responsible for the scientific and technical direction of the entire clinical study.

Principal Investigator
Priscilla K. Brastianos, MD
Principal Investigator Affiliation Massachusetts General Hospital

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Agency Class
OtherNIH
Overall Status Recruiting
Countries United States

The disease, disorder, syndrome, illness, or injury that is being studied.

Conditions
BRAF V600E Mutation Present, Papillary Craniopharyngioma
Additional Details

PRIMARY OBJECTIVES:

  • I. To determine the activity of BRAF and MEK inhibitor combination in untreated papillary craniopharyngiomas as measured by best response at any time during the first four cycles of BRAF and MEK inhibitor treatment.
  • II. To determine the activity of BRAF and MEK inhibitor combination in papillary craniopharyngiomas that have progressed after prior radiation treatment with or without surgical resection as measured by best response at any time during the first four cycles of BRAF and MEK inhibitor treatment.
SECONDARY OBJECTIVES:
  • I. To determine the progression-free survival of patients with papillary craniopharyngiomas receiving BRAF and MEK inhibitors.
  • II. To determine the toxicity of BRAF/MEK inhibitors in patients with papillary craniopharyngiomas.
  • III. To determine the activity of BRAF and MEK inhibitor combination in papillary craniopharyngiomas as measured by response of enhancing volume of craniopharyngioma.
  • IV. To determine the activity of BRAF and MEK inhibitor combination in papillary craniopharyngiomas as measured by response of nonenhancing volume of craniopharyngioma.
  • V. To determine the overall survival of patients with papillary craniopharyngiomas receiving BRAF and MEK inhibitors.
  • VI. To determine the duration of response in patients with papillary craniopharyngiomas receiving BRAF and MEK inhibitors.
TERTIARY OBJECTIVES:
  • I. To evaluate visual fields in patients with papillary craniopharyngiomas who have received BRAF/MEK inhibitors.
  • II. To evaluate pituitary hormone replacement over time in patients with papillary craniopharyngiomas who have received BRAF/MEK inhibitors.
  • III. To evaluate the time to response in patients with papillary craniopharyngiomas receiving BRAF and MEK inhibitors.
  • IV. To assess toxicity that may be associated with radiotherapy in patients with papillary craniopharyngiomas who have received BRAF/MEK inhibitors.
  • V. To evaluate molecular biomarkers of response in papillary craniopharyngiomas.
  • VI. To evaluate circulating tumor cells and cell-free circulating deoxyribonucleic acid (DNA) in patients with papillary craniopharyngiomas.
OUTLINE: Patients receive vemurafenib orally (PO) twice daily (BID) on day 1-28 and cobimetinib PO once daily (QD) on days 1-21. Treatment repeats every 28 days for up to 5 courses in the absence of disease progression or unacceptable toxicity. Patients may then receive radiation therapy, surgery, or continued treatment with vemurafenib and cobimetinib at the discretion of the treating physician. After completion of study treatment, patients with disease progression are followed up every 16 weeks for 2 years and all other patients are followed up every 6 months for 5 years.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

Birmingham, Alabama

Status

Recruiting

Address

University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233

Site Contact

Site Public Contact

tmyrick@uab.edu

205-934-0220

Auburn, California

Status

Recruiting

Address

Sutter Cancer Centers Radiation Oncology Services-Auburn

Auburn, California, 95603

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Berkeley, California

Status

Recruiting

Address

Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Mills-Peninsula Medical Center, Burlingame, California

Status

Recruiting

Address

Mills-Peninsula Medical Center

Burlingame, California, 94010

Site Contact

Site Public Contact

PazE@sutterhealth.org

650-696-4487

Cameron Park, California

Status

Recruiting

Address

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Cameron Park, California, 95682

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Eden Hospital Medical Center, Castro Valley, California

Status

Recruiting

Address

Eden Hospital Medical Center

Castro Valley, California, 94546

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Memorial Medical Center, Modesto, California

Status

Recruiting

Address

Memorial Medical Center

Modesto, California, 95355

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Mountain View, California

Status

Recruiting

Address

Palo Alto Medical Foundation-Camino Division

Mountain View, California, 94040

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Orange, California

Status

Recruiting

Address

UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868

Site Contact

Site Public Contact

ucstudy@uci.edu

877-827-8839

Palo Alto Medical Foundation Health Care, Palo Alto, California

Status

Recruiting

Address

Palo Alto Medical Foundation Health Care

Palo Alto, California, 94301

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Roseville, California

Status

Recruiting

Address

Sutter Cancer Centers Radiation Oncology Services-Roseville

Roseville, California, 95661

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Sutter Roseville Medical Center, Roseville, California

Status

Recruiting

Address

Sutter Roseville Medical Center

Roseville, California, 95661

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Sutter Medical Center Sacramento, Sacramento, California

Status

Recruiting

Address

Sutter Medical Center Sacramento

Sacramento, California, 95816

Site Contact

Site Public Contact

cancerinfo@sutterhealth.org

916-454-6500

San Francisco, California

Status

Recruiting

Address

California Pacific Medical Center-Pacific Campus

San Francisco, California, 94115

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California

Status

Recruiting

Address

Palo Alto Medical Foundation-Sunnyvale

Sunnyvale, California, 94086

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Vacaville, California

Status

Recruiting

Address

Sutter Cancer Centers Radiation Oncology Services-Vacaville

Vacaville, California, 95687

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Vallejo, California

Status

Recruiting

Address

Sutter Solano Medical Center/Cancer Center

Vallejo, California, 94589

Site Contact

Site Public Contact

bernicl@sutterhealth.org

415-209-2686

Miami, Florida

Status

Recruiting

Address

University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136

Site Contact

Site Public Contact

pbrastianos@partners.org

305-243-2647

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Status

Recruiting

Address

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706

Site Contact

Site Public Contact

stephanie.couch@stjoeshealth.org

734-712-3671

Caldwell, Idaho

Status

Recruiting

Address

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605

Site Contact

Site Public Contact

stephanie.couch@stjoeshealth.org

734-712-3671

Idaho Urologic Institute-Meridian, Meridian, Idaho

Status

Recruiting

Address

Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642

Site Contact

Site Public Contact

stephanie.couch@stjoeshealth.org

734-712-3671

Kootenai Cancer Center, Post Falls, Idaho

Status

Recruiting

Address

Kootenai Cancer Center

Post Falls, Idaho, 83854

Site Contact

Site Public Contact

mccinfo@mtcancer.org

406-969-6060

Rush University Medical Center, Chicago, Illinois

Status

Recruiting

Address

Rush University Medical Center

Chicago, Illinois, 60612

Site Contact

Site Public Contact

clinical_trials@rush.edu

312-942-5498

Central Care Cancer Center - Garden City, Garden City, Kansas

Status

Recruiting

Address

Central Care Cancer Center - Garden City

Garden City, Kansas, 67846

Site Contact

Site Public Contact

aroland@kccop.org

913-948-5588

Central Care Cancer Center - Great Bend, Great Bend, Kansas

Status

Recruiting

Address

Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530

Site Contact

Site Public Contact

aroland@kccop.org

913-948-5588

Baltimore, Maryland

Status

Recruiting

Address

Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287

Site Contact

Site Public Contact

jhcccro@jhmi.edu

410-955-8804

Boston, Massachusetts

Status

Recruiting

Address

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114

Site Contact

Site Public Contact

pbrastianos@partners.org

877-726-5130

Dana-Farber Cancer Institute, Boston, Massachusetts

Status

Recruiting

Address

Dana-Farber Cancer Institute

Boston, Massachusetts, 02215

Site Contact

Site Public Contact

pbrastianos@partners.org

877-442-3324

Ann Arbor, Michigan

Status

Recruiting

Address

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109

Site Contact

Site Public Contact

pbrastianos@partners.org

800-865-1125

Bronson Battle Creek, Battle Creek, Michigan

Status

Recruiting

Address

Bronson Battle Creek

Battle Creek, Michigan, 49017

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Grand Rapids, Michigan

Status

Recruiting

Address

Helen DeVos Children's Hospital at Spectrum Health

Grand Rapids, Michigan, 49503

Site Contact

Site Public Contact

protocols@AllianceNCTN.org

773-702-9171

Mercy Health Saint Mary's, Grand Rapids, Michigan

Status

Recruiting

Address

Mercy Health Saint Mary's

Grand Rapids, Michigan, 49503

Site Contact

Site Public Contact

protocols@AllianceNCTN.org

773-702-9171

Spectrum Health at Butterworth Campus, Grand Rapids, Michigan

Status

Recruiting

Address

Spectrum Health at Butterworth Campus

Grand Rapids, Michigan, 49503

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Bronson Methodist Hospital, Kalamazoo, Michigan

Status

Recruiting

Address

Bronson Methodist Hospital

Kalamazoo, Michigan, 49007

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

West Michigan Cancer Center, Kalamazoo, Michigan

Status

Recruiting

Address

West Michigan Cancer Center

Kalamazoo, Michigan, 49007

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Borgess Medical Center, Kalamazoo, Michigan

Status

Recruiting

Address

Borgess Medical Center

Kalamazoo, Michigan, 49048

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Mercy Health Mercy Campus, Muskegon, Michigan

Status

Recruiting

Address

Mercy Health Mercy Campus

Muskegon, Michigan, 49444

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Lakeland Hospital Niles, Niles, Michigan

Status

Recruiting

Address

Lakeland Hospital Niles

Niles, Michigan, 49120

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

269-556-2880

Spectrum Health Reed City Hospital, Reed City, Michigan

Status

Recruiting

Address

Spectrum Health Reed City Hospital

Reed City, Michigan, 49677

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Lakeland Medical Center Saint Joseph, Saint Joseph, Michigan

Status

Recruiting

Address

Lakeland Medical Center Saint Joseph

Saint Joseph, Michigan, 49085

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

800-865-7884

Marie Yeager Cancer Center, Saint Joseph, Michigan

Status

Recruiting

Address

Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Munson Medical Center, Traverse City, Michigan

Status

Recruiting

Address

Munson Medical Center

Traverse City, Michigan, 49684

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Metro Health Hospital, Wyoming, Michigan

Status

Recruiting

Address

Metro Health Hospital

Wyoming, Michigan, 49519

Site Contact

Site Public Contact

crcwm-regulatory@crcwm.org

616-391-1230

Fairview Ridges Hospital, Burnsville, Minnesota

Status

Recruiting

Address

Fairview Ridges Hospital

Burnsville, Minnesota, 55337

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Mercy Hospital, Coon Rapids, Minnesota

Status

Recruiting

Address

Mercy Hospital

Coon Rapids, Minnesota, 55433

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Fairview-Southdale Hospital, Edina, Minnesota

Status

Recruiting

Address

Fairview-Southdale Hospital

Edina, Minnesota, 55435

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Unity Hospital, Fridley, Minnesota

Status

Recruiting

Address

Unity Hospital

Fridley, Minnesota, 55432

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Fairview Maple Grove Medical Center, Maple Grove, Minnesota

Status

Recruiting

Address

Fairview Maple Grove Medical Center

Maple Grove, Minnesota, 55369

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Maplewood, Minnesota

Status

Recruiting

Address

Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Saint John's Hospital - Healtheast, Maplewood, Minnesota

Status

Recruiting

Address

Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109

Site Contact

Site Public Contact

protocols@AllianceNCTN.org

773-702-9171

Abbott-Northwestern Hospital, Minneapolis, Minnesota

Status

Recruiting

Address

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Hennepin County Medical Center, Minneapolis, Minnesota

Status

Recruiting

Address

Hennepin County Medical Center

Minneapolis, Minnesota, 55415

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Health Partners Inc, Minneapolis, Minnesota

Status

Recruiting

Address

Health Partners Inc

Minneapolis, Minnesota, 55454

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Monticello Cancer Center, Monticello, Minnesota

Status

Recruiting

Address

Monticello Cancer Center

Monticello, Minnesota, 55362

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

North Memorial Medical Health Center, Robbinsdale, Minnesota

Status

Recruiting

Address

North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Mayo Clinic, Rochester, Minnesota

Status

Recruiting

Address

Mayo Clinic

Rochester, Minnesota, 55905

Site Contact

Site Public Contact

pbrastianos@partners.org

855-776-0015

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

Status

Recruiting

Address

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Regions Hospital, Saint Paul, Minnesota

Status

Recruiting

Address

Regions Hospital

Saint Paul, Minnesota, 55101

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

United Hospital, Saint Paul, Minnesota

Status

Recruiting

Address

United Hospital

Saint Paul, Minnesota, 55102

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Saint Francis Regional Medical Center, Shakopee, Minnesota

Status

Recruiting

Address

Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Lakeview Hospital, Stillwater, Minnesota

Status

Recruiting

Address

Lakeview Hospital

Stillwater, Minnesota, 55082

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Ridgeview Medical Center, Waconia, Minnesota

Status

Recruiting

Address

Ridgeview Medical Center

Waconia, Minnesota, 55387

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Rice Memorial Hospital, Willmar, Minnesota

Status

Recruiting

Address

Rice Memorial Hospital

Willmar, Minnesota, 56201

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Woodbury, Minnesota

Status

Recruiting

Address

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

Central Care Cancer Center - Bolivar, Bolivar, Missouri

Status

Recruiting

Address

Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613

Site Contact

Site Public Contact

aroland@kccop.org

800-328-6010

Research Medical Center, Kansas City, Missouri

Status

Recruiting

Address

Research Medical Center

Kansas City, Missouri, 64132

Site Contact

Site Public Contact

aroland@kccop.org

913-948-5588

Washington University School of Medicine, Saint Louis, Missouri

Status

Recruiting

Address

Washington University School of Medicine

Saint Louis, Missouri, 63110

Site Contact

Site Public Contact

info@siteman.wustl.edu

800-600-3606

Billings Clinic Cancer Center, Billings, Montana

Status

Recruiting

Address

Billings Clinic Cancer Center

Billings, Montana, 59101

Site Contact

Site Public Contact

research@billingsclinic.org

800-996-2663

Bozeman Deaconess Hospital, Bozeman, Montana

Status

Recruiting

Address

Bozeman Deaconess Hospital

Bozeman, Montana, 59715

Site Contact

Site Public Contact

mccinfo@mtcancer.org

406-969-6060

Great Falls, Montana

Status

Recruiting

Address

Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405

Site Contact

Site Public Contact

mccinfo@mtcancer.org

406-969-6060

Kalispell Regional Medical Center, Kalispell, Montana

Status

Recruiting

Address

Kalispell Regional Medical Center

Kalispell, Montana, 59901

Site Contact

Site Public Contact

mccinfo@mtcancer.org

406-969-6060

Community Medical Hospital, Missoula, Montana

Status

Recruiting

Address

Community Medical Hospital

Missoula, Montana, 59804

Site Contact

Site Public Contact

mccinfo@mtcancer.org

406-969-6060

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Status

Suspended

Address

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756

NYP/Weill Cornell Medical Center, New York, New York

Status

Recruiting

Address

NYP/Weill Cornell Medical Center

New York, New York, 10065

Site Contact

Site Public Contact

pbrastianos@partners.org

212-746-1848

Chapel Hill, North Carolina

Status

Recruiting

Address

UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599

Site Contact

Site Public Contact

cancerclinicaltrials@med.unc.edu

877-668-0683

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Status

Recruiting

Address

Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157

Site Contact

Site Public Contact

pbrastianos@partners.org

336-713-6771

M D Anderson Cancer Center, Houston, Texas

Status

Recruiting

Address

M D Anderson Cancer Center

Houston, Texas, 77030

Site Contact

Site Public Contact

askmdanderson@mdanderson.org

877-632-6789

Farmington Health Center, Farmington, Utah

Status

Recruiting

Address

Farmington Health Center

Farmington, Utah, 84025

Site Contact

Site Public Contact

cancerinfo@hci.utah.edu

888-424-2100

Salt Lake City, Utah

Status

Recruiting

Address

Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112

Site Contact

Site Public Contact

cancerinfo@hci.utah.edu

888-424-2100

South Jordan Health Center, South Jordan, Utah

Status

Recruiting

Address

South Jordan Health Center

South Jordan, Utah, 84009

Site Contact

Site Public Contact

cancerinfo@hci.utah.edu

888-424-2100

Fred Hutchinson Cancer Research Center, Seattle, Washington

Status

Recruiting

Address

Fred Hutchinson Cancer Research Center

Seattle, Washington, 98109

Site Contact

Site Public Contact

pbrastianos@partners.org

800-804-8824

Seattle Cancer Care Alliance, Seattle, Washington

Status

Recruiting

Address

Seattle Cancer Care Alliance

Seattle, Washington, 98109

Site Contact

Site Public Contact

pbrastianos@partners.org

800-804-8824

University of Washington Medical Center, Seattle, Washington

Status

Recruiting

Address

University of Washington Medical Center

Seattle, Washington, 98195

Site Contact

Site Public Contact

pbrastianos@partners.org

800-804-8824

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Status

Suspended

Address

Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215

Cancer Center of Western Wisconsin, New Richmond, Wisconsin

Status

Recruiting

Address

Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017

Site Contact

Site Public Contact

mmcorc@healthpartners.com

952-993-1517

The content provided by NBTS on clinical trials is for informational purposes only and is not a substitute for medical consultation with your healthcare provider. We do not recommend or endorse any specific study and you are advised to discuss the information shown with your healthcare provider. While we believe the information presented on this website to be accurate at the time of writing, we do not guarantee that its contents are correct, complete, or applicable to any particular individual situation. We strongly encourage individuals to seek out appropriate medical advice and treatment from their physicians. We cannot guarantee the availability of any clinical trial listed and will not be responsible if you are considered ineligible to participate in a given clinical trial. We are also not liable for any injury arising as a result of participation. For a full description of terms please refer to: Terms, Conditions & Privacy